* More than 35 years of experience* Consultant Nephrologist, The Sainsbury Wing, Hammersmith Hospital, London (present) * Consultant Nephrologist, Centennial Medical Centre, Elstree (present)* Professor of Renal Medicine, Imperial College London (present)* â‚¬â€¹Reader in Renal Medicine and Honorary Consultant Physician, Imperial College London (2011 - 2014) ...

* Graduated in Medicine, University of London (1983) - second highest mark in whole university* PhD in Immunology, University College London (1993) * FRCP Royal College Physicians 1996* MRCP(UK) Royal College Physicians 1986* GMC Specialist Register in Renal and General Medicine 1995 GMC Number 2838490; Revalidated 2015 ...

* Fellow of the Royal College of Physicians of London* Elected member of the UK Renal Association Executive 2009-2012 * Previous member of Renal Association Clinical Affairs Board, Education and Training Committee* Active member of the Equal Opportunities in Nephrology Committee ...

* Senior Scholar, Kings College Hospital Medical School 1983* MB BS(Hons) Proxime accessit (Runner up to the Gold Medallist), University of London 1983 * 1988-1991 MRC Clinical Training Fellow, ICRF Tumour Immunology Unit, UCL (Supervisor: Professor Av Mitchison)* 1991-1995 MRC Clinician Scientist Training Fellow, Dept of Immunology, Royal Postgraduate Medical School (Supervisor: Professor Robert Lechler). ...

* Turner-Stokes T, Wilson H, Morreale M, Nunes A, Cairns T, Cook T, Pusey C, Tarzi R and Lightstone L Positive ANCA serology in patients with lupus nephritis is associated with distinct histopathological features on renal biopsy Kidney Int 2017 PMID: 28750930* Lightstone L and Hladunewich MA Lupus Nephritis and Pregnancy: Concerns and Management 2017 Semin Nephrol PMID 28711073 * Beckwith H, Medjeral-Thomas N, Galliford J, Griffith M, Levy J, Lightstone L, Palmer A, Roufosse C, Pusey C, Cook HT, Cairns T Mycophenolate mofetil therapy in immunoglobulin A nephropathy: histological changes after treatment Nephrol Dial Transplant 2017; 32(suppl1): 123-128* Stratigou V, Doyle AF, Carlucci F, Stephens L, Foschi V, Castelli M, McKenna N, Cook HT, Lightstone L, Cairns TD, Pickering MC, Botto M Altered expression of signalling lymphocyte activation molecule receptors in T cells from lupus nephritis patients €“ a potential biomarker of disease activity Rheumatology (Oxford) 2017 PMID: 28387859* Webster P, Lightstone L, McKay D, Josephson MA. Pregnancy in chronic kidney disease and kidney transplantation. Kidney Int. 2017; 91:1047-56* Webster P, Webster LM, Cook HT, Horsfield C, Seed, PT, Vaz R, Santos C, Lydon I, Homsy M, Lightsone L and Bramham K A multicentre cohort study of histological findings and long-term outcomes of kidney disease in women who have been pregnant Clin J Am Soc Nephrol 2017; 12:408-16* Webster P, Nelson-Piercy C, and Lightstone L A complicated multisystem flare of systemic lupus erythematosus during pregnancy BMJ Case Reports 2017; doi: 10-1136/bcr-2016-217546* Miloslavsky EM, Naden RP, Bijlsma JW, Brogan PA, Brown ES, Brunetta P, Buttgereit F, Choi HK, DiCaire JF, Gelfand JM, Heaney LG, Lightstone L, Lu N, Murrell DF, Petri M, Rosenbaum JT, Saag KS, Urowitz MB, Winthrop KL, Stone JH Development of a glucocorticoid toxicity index (GTI) using multicriteria decision analysis Ann Rheum Dis 2017; 76:543-546* Anders H-J, Rovin B, Jayne D, Brunetta P, Coppo R, Davidson A, Devarapu SK, de Zeeuw D, Duffield J, Eulberg D, Feirro A, Floege J, Frese S, Guillevin L, Holdsworth S, Hughes J, Kettritz R, Kluger M, Krebs C, Lapteva Larissa, Levin A, Li J, Lightstone L et al; ISN Nexus 2016 Symposia: Translational Immunology in Kidney Disease €“ The Berlin Roadmap Kidney Int Reports. 2016; 1:327-339* Bramham K, Seed PT, Lightstone L, Nelson-Piercy C, Gill C, Webster P, Poston L, and Chappel L Diagnostic and predictive biomarkers for pre-eclampsia in patients with established hypertension and chronic kidney disease. Kidney Int. 2016; 89:874-85* Wilhelmus S, Bajema IM, Bertsias GK, Boumpas DT, Gordon C, Lightstone L, et al. Lupus nephritis management guidelines compared. Nephrol Dial Transplant 2016; 31:904-13* Pickering MC, Ismajli M, Condon MB, McKenna N, Hall AE, Lightstone L, et al. Eculizumab as rescue therapy in severe resistant lupus nephritis. Rheumatology (Oxford). 2015;54:2286-8* Ambrose N, Khan E, Ravindran R, Lightstone L, Abraham S, Botto M, et al. The exaggerated inflammatory response in Behcet's syndrome: identification of dysfunctional post-transcriptional regulation of the IFN-gamma/CXCL10 IP-10 pathway. Clin Exp Immunol 2015;181:427-33* Beckwith H, Lightstone L. Rituximab in systemic lupus erythematosus and lupus nephritis. Nephron Clin Practice. 2014;128:250-4.* McAdoo SP, Tanna A, Randone O, Tam FW, Tarzi RM, Levy JB, et al. Necrotizing and crescentic glomerulonephritis presenting with preserved renal function in patients with underlying multisystem autoimmune disease: a retrospective case series. Rheumatology (Oxford). 2015;54(6):1025-32* Webster P, Wardle A, Bramham K, Webster L, Nelson-Piercy C, Lightstone L. Tacrolimus is an effective treatment for lupus nephritis in pregnancy. Lupus. 2014;23(11):1192-6* Griffin B, Lightstone L. Renoprotective strategies in lupus nephritis: beyond immunosuppression. Lupus. 2013;22(12):1267-73* Arulkumaran N, Lightstone L. Severe pre-eclampsia and hypertensive crises. Best practice and research Clin Obstet Gynaecol. 2013;27:877-84* Condon MB, Ashby D, Pepper RJ, Cook HT, Levy JB, Griffith M, et al. Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids. Ann Rheum Dis. 2013;72:1280-6* Lightstone L. Minimising steroids in lupus nephritis--will B cell depletion pave the way? Lupus. 2013;22:390-9* Bramham K, Chusney G, Lee J, Lightstone L, Nelson-Piercy C. Breastfeeding and tacrolimus: serial monitoring in breast-fed and bottle-fed infants. Clin J Am Soc Nephrol 2013;8:563-7* Lawrence C, Cook HT, and Lightstone L Seasonal relapsing minimal change disease: a novel strategy for avoiding long-term immunosuppression Case Report Nephrol Urol 2012; 2:102-7* Wilkinson E, Randhawa G, Feehally J, Farrington K, Greenwood R, Choi P, Lightstone L. A multi-centre qualitative study exploring the experiences of UK South Asian and White diabetic patients referred for renal care. BMC Nephrol 2012; 13: 157* Bertsias GK, Tektonidou M, Amoura Z, et al. Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis. 2012; 71: 1771-82* Okada Y, Sim X, Go MJ, et al. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet. 2012;44: 904-9. (Kidney Gen consortium member)* Bramham K, Lightstone L. Pre-pregnancy counselling for women with CKD. J Nephrol. 2012;25:450-9.* RECENT KEYNOTE AND INVITED TALKS* 2017 All India Institute of Medical Sciences (AIIMS) €“ Glomerulonephritis Conclave, Faculty* 2017 Irish Society of Nephrology - Managing lupus nephritis in the 21st century* 2016 UK Kidney Week 2016 €“ Chandos Lecture; Renal Disease and Pregnancy* Am Society Nephrol Kidney Week: 2016, 2017: Early program on Glomerular Disease; talk on Pregnancy and Glomerular Disease 2016: Plenary talk on lupus nephritis 2015: Clinical discussant, clinicopathological symposium; 2015: Early program on Women€™s Health and Renal Disease; Lupus nephritis and pregnancy* American College Rheumatology annual meeting  2016: ISN Nexus meeting on Translational Immunology in Kidney Disease chair and speaker on lupus nephritis 2014-16: Meet the Professor €“ Novel approaches to treating lupus nephritis 2014: Plenary Talk: Long term Rituxilup data* World Congresses: 2013: Lupus 2013, Steroid minimizing in lupus; The renal biopsy for the non histopathologist 2014: Fetal Medicine 2014, Renal disease and pregnancy 2015: Nephrology 2015; Renal disease and pregnancy* OTHER INVITED TALKS* 2017: Controversies in Rheumatology and Autoimmunity; chair, and debated €œSteroids can be minimized in lupus nephritis€.* 2016: Society Obstetric Med Aus NZ annual meeting (SOMANZ), joint with Internal Med; Panel discussion difficult cases; 2 plenary talks* 2015, 2016: EU Lupus Meeting* 2016: Kolkata Lupus Initiative, 2 plenary talks* 2013, 14, 16: Lupus Academy; Modern management of lupus nephritis * 2011, 14, 16: Ten Topics in Rheumatology  ...

* Co-chair of UK Renal Association Glomerulonephritis Clinical Study Group - 2015 onwards* Chief Investigator on the international multicentre randomised RITUXILUP trial funded by Arthritis UK * Established and runs a renal obstetric clinic, and a preconception counselling clinic for women with kidney disease* Member of the External Referee Panel, Lupus UK (2010 - 2015)* Medical Advisor to Lupus UK 20156 onwards* 2009-2015 Clinical Expert, NICE STA of Belimumab for the treatment of lupus* 2013 €“ date National Coordinator, Pregnancy and Chronic Kidney Disease Rare Disease Group, Jan 2013 to Dec 2014, remain as committee member Dec 14 onwards* 2012- date Academic Lead for Renal Training, NW London Renal Training Programme and member of Imperial College Faculty of Medicine Postgraduate Clinical Academic Training Committee since 2010.* 2016 €“ date Co-opted Renal Expert on NICE Guideline on the Intrapartum Care of the High Risk Pregnancy ...

* Interim Director, North West Thames Foundation School, Imperial College London (2009 - 2012)* Director of the Academic Foundation Programme, North West Thames Foundation School, Imperial College London (2009-2015) * Has major roles in undergraduate and postgraduate medicine at Imperial College London* Runs various postgraduate short courses including annual Short Course in Immunology, Short course in Glomerular Diseases* Invited speaker and teacher at numerous national and international courses and symposia - recent examples below* Since 2007: Medical Complications in Pregnancy €“ annual talk on Renal disease and pregnancy* Since 2009: UK Renal Association Advanced Nephrology Course; Renal disease and pregnancy* Since 2009: Annual Imperial Renal Path course-co-organise, chair, speak; Lupus nephritis* 2010: Imperial Lupus Meeting€“ Course organiser and speaker ...